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Antonopoulou Smaragdi

Professor - Biochemistry Lipids

Expert

Her research experience is mainly focused on lipid metabolism and Platelet- Activating Factor (PAF), on biochemical mechanisms of pathophysiological conditions, methods of isolation, purification and identification of lipids from natural sources (biological samples, foods, plants and animals), utilization of olive-oil, wineries and fisheries by-products into high added value products as well as on the relation between Traditionally Greek Diet (usually referred as Mediterranean Diet) and cardiovascular diseases.

Education

  • PhD (Department of Chemistry, NKUA, 1994)
  • BSc Chemistry (Department of Chemistry, NKUA, 1988)]

Research Interests

  • Biochemical mechanisms of pathophysiological conditions
  • Lipid metabolism and Platelet- Activating Factor (PAF)
  • Methods of isolation, purification and identification of lipids from natural sources (biological samples, foods, plants and animals)
  • Mediterranean Diet, food microconstituents and inflammatory diseases
  • Utilization of olive-oil, wineries and fisheries by-products into high added value products

Publications

  • Ntzouvani A, Antonopoulou S, Fragopoulou E, Kontogianni MD, Nomikos T, Mikellidi A, Xanthopoulou M, Kalogeropoulos N, Panagiotakos D. Effect of differently fed farmed gilthead sea bream consumption on platelet aggregation and circulating haemostatic markers among apparently healthy adults: a double-blind randomized crossover trial. Nutrients 2021;13(2):286. doi: 10.3390/nu13020286. https://pubmed.ncbi.nlm.nih.gov/33498445/
  • Demopoulos CA, Antonopoulou S, Theoharides TC. CoVid-19, microthromboses, inflammation and Platelet Activating Factor (PAF). Biofactors 2020; 46(6):927-933. doi: 10.1002/biof.1696. https://pubmed.ncbi.nlm.nih.gov/33296106/
  • Ntzouvani A, Nomikos T, Panagiotakos D, Fragopoulou E, Pitsavos C, McCann A, Ueland PM, Antonopoulou S. Amino acid profile and metabolic syndrome in a male Mediterranean population: A cross-sectional study. Nutr Metab Cardiovasc Dis 2017; 27(11):1021-1030. doi: 10.1016/j.numecd.2017.07.006. https://pubmed.ncbi.nlm.nih.gov/28958693/
  • Kelesidis T, Papakonstantinou V, Detopoulou P, Fragopoulou E, Chini M, Lazanas MC, Antonopoulou S. The role of platelet-activating factor in chronic inflammation, immune activation, and comorbidities associated with HIV infection. AIDS Rev 2015;17(4):191-201. https://pubmed.ncbi.nlm.nih.gov/26616844/
  • Vlachogianni IC, Fragopoulou E, Stamatakis GM, Kostakis IK, Antonopoulou S. Platelet Activating Factor (PAF) biosynthesis is inhibited by phenolic compounds in U-937 cells under inflammatory conditions. Prostaglandins Other Lipid Mediat 2015;121(Pt B):176-83. doi: 10.1016/j.prostaglandins.2015.09.001. https://pubmed.ncbi.nlm.nih.gov/26358846/
  • Detopoulou P, Fragopoulou E, Nomikos T, Yannakoulia M, Stamatakis G, Panagiotakos DB, Antonopoulou S. The relation of diet with PAF and its metabolic enzymes in healthy volunteers. Eur J Nutr 2015;54(1):25-34. doi: 10.1007/s00394-014-0682-3. https://pubmed.ncbi.nlm.nih.gov/24639073/