e-class
dedousi[@]hua.gr
+30 210 9549 304
Office: Lab of Biology - Building: B
Download CV

Dedoussis Georgios

Professor - Molecular genetics-Nutrigenetics

Expert

Georgios Dedoussis has worked as a researcher on a Fulbright scholarship at the Medical Faculty of the ‘Harvard University’ (Boston, USA). In 2018 he received “The Gutenberg Chair” from the Region Grand Est, Euro metropole de Strasbourg. He has published more than 300 papers and his research work has been recognized by others (number of citations > 55000, h-index: 85). He was nominated in 2019 among the most cited scientists worldwide during the last decade.

Education

  • PhD Thesis. “Phenotypic and functional characterization of tumor infiltrating lymphocytes in breast cancer”. Medical School of Athens, 1995.
  • D.E.A of Biotechnology, Microbiology et Bioconversion, University of Compiegne, France. Title of research project: “Production of human monoclonal antibodies against tumor antigens in breast cancer”, Compiegne, France, 1990
  • Bachelor of Biology, University of Patras, 1988

Research Interests

  • I have coordinated many national and European grants in the field of the molecular genetics/nutrigenetics of obesity, lipid levels, myocardial infraction and Non-Alcoholic Fatty Liver Disease (NAFLD).
  • My group has a strong expertise on Genome Wide Association analysis, by applying bioinformatic tools for the identification of genetic variants associated with chronic diseases.
  • We are exploring lifestyle and genetic predictors for assessing personalized recommendations.
  • We are also testing the impact of natural compounds on NAFLD patients and I was the coordinator of a Marie Curie RISE European grant (www.MAST4HEALTH.eu)

Publications

  • Amerikanou C, Kanoni S, Kaliora AC, Barone A, Bjelan M, D'Auria G, Gioxari A, Gosalbes MJ, Mouchti S, Stathopoulou MG, Soriano B, Stojanoski S, Banerjee R, Halabalaki M, Mikropoulou EV, Kannt A, Lamont J, Llorens C, Marascio F, Marascio M, Roig FJ, Smyrnioudis I, Varlamis I, Visvikis-Siest S, Vukic M, Milic N, Medic-Stojanoska M, Cesarini L, Campolo J, Gastaldelli A, Deloukas P, Trivella MG, Francino MP, Dedoussis GV; MAST4HEALTH consortium. Effect of Mastiha supplementation on NAFLD: The MAST4HEALTH Randomised, Controlled Trial. Mol Nutr Food Res. 2021 May;65(10):e2001178. doi: 10.1002/mnfr.202001178.
  • Kafyra M, Kalafati IP, Kumar S, Kontoe MS, Masson C, Siest S, Dedoussis GV. Dietary Patterns, Blood Pressure and the Glycemic and Lipidemic Profile of Two Teenage, European Populations. Nutrients. 2021 Jan 10;13(1):198. doi: 10.3390/nu13010198.
  • Gilly A, Park YC, Png G, Barysenka A, Fischer I, Bjørnland T, Southam L, Suveges D, Neumeyer S, Rayner NW, Tsafantakis E, Karaleftheri M, Dedoussis G, Zeggini E. Whole-genome sequencing analysis of the cardiometabolic proteome. Nat Commun. 2020 Dec 10;11(1):6336. doi: 10.1038/s41467-020-20079-2.
  • Katsareli EA, Amerikanou C, Rouskas K, Dimopoulos A, Diamantis T, Alexandrou A, Griniatsos J, Bourgeois S, Dermitzakis E, Ragoussis J, Dimas AS, Dedoussis GV. A Genetic Risk Score for the Estimation of Weight Loss After Bariatric Surgery. Obes Surg. 2020 Apr;30(4):1482-1490. doi: 10.1007/s11695-019-04320-6.
  • Gilly A, Southam L, Suveges D, Kuchenbaecker K, Moore R, Melloni GEM, Hatzikotoulas K, Farmaki AE, Ritchie G, Schwartzentruber J, Danecek P, Kilian B, Pollard MO, Ge X, Tsafantakis E, Dedoussis G, Zeggini E. Very low-depth whole-genome sequencing in complex trait association studies. Bioinformatics. 2019 Aug 1;35(15):2555-2561. doi: 10.1093/bioinformatics/bty1032.
  • Grarup N, Moltke I, Andersen MK, Dalby M, Vitting-Seerup K, Kern T, Mahendran Y, Jørsboe E, Larsen CVL, Dahl-Petersen IK, Gilly A, Suveges D, Dedoussis G, Zeggini E, Pedersen O, Andersson R, Bjerregaard P, Jørgensen ME, Albrechtsen A, Hansen T. Loss-of-function variants in ADCY3 increase risk of obesity and type 2 diabetes. Nat Genet. 2018 Feb;50(2):172-174. doi: 10.1038/s41588-017-0022-7.